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Recombinant Influenza A H3N2 Matrix Protein 2 Ectodomain (M2e), N-GST and C-His

Cat. No.VG3F35

Product TypeVeterinary Antigens

Size

Product Overview

BioVenic's Recombinant Influenza A H3N2 Matrix Protein 2 Ectodomain (M2e), N-GST and C-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 31.0 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Virus
Expression System E.coli Expression System
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 31.0 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

M2e is the highly conserved 23-amino acid N-terminal extracellular domain of the M2 ion channel in Influenza A (H3N2). While the viral surface glycoproteins HA and NA undergo frequent antigenic drift, the M2e sequence remains remarkably stable across seasonal H3N2 strains. In the H3N2 subtype, M2e serves as a critical target for "universal" vaccine strategies. Antibodies directed against H3N2 M2e facilitate the clearance of infected host cells through Fc-mediated effector functions, such as antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis, providing broad heterosubtypic protection.

Protein Influenza A H3N2 Matrix Protein 2 Ectodomain (M2e)
Protein Synonym M2e; H3N2 Matrix protein 2 ectodomain; M2 extracellular domain; sM2e (soluble M2e); Matrix 2 protein N-terminal domain

Shipping and Storage

This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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