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Recombinant Helicobacter pylori Serine Protease (HtrA), C-His

Cat. No.VG9C220

Product TypeVeterinary Antigens

Size

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Product Overview

BioVenic's Recombinant Helicobacter pylori Serine Protease (HtrA), C-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 49.1 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bacterium
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 49.1 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

In the veterinary field, the function of Helicobacter pylori Serine protease (HtrA) is primarily as a significant pathogenic factor that can disrupt host cell junctions and facilitate bacterial transmigration. By cleaving cell adhesion molecules such as E-cadherin, HtrA weakens the barrier function of gastric epithelial cells, making it easier for bacteria to invade host tissues. Research on this function helps in developing prevention and treatment strategies against H. pylori infection.

Protein Helicobacter pylori Serine Protease (HtrA)
Protein Synonym Periplasmic serine endoprotease DegP-like
UniProt ID O25663

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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