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Recombinant Feline Transforming Growth Factor Beta-2 (TGFB2)
Product Overview
BioVenic's Recombinant Feline Transforming Growth Factor Beta-2 (TGFB2) is a recombinant protein expressed from Mammalian expression system. Its predicted molecular weight is 13 kDa. The purity is greater than 95% (SDS-PAGE). The endotoxin level is <0.01 EU/μg (LAL).
Specifications
Target Information
Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and plays a vital role during embryonic development. TGF-β has been implicated in the pathogenesis of a variety of ocular diseases. A previous study identified increased local ocular production of TGF-β2 with a robust positive association with intraocular pressure in a spontaneous feline glaucoma model.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -20°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -20°C for 3 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Dissolve the lyophilized protein in distilled water. Avoid mixing by vortexing or pipetting. It is not recommended to reconstitute to a concentration < 100 μg/mL. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Oikawa, K. et al. Aqueous Humor TGF-β2 and Its Association With Intraocular Pressure in a Naturally Occurring Large Animal Model of Glaucoma. Investigative ophthalmology & visual science. 2023, 64: 18-18.