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Recombinant Feline Thyrotropin Receptor (TSHR)

Cat. No.AP2C241

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Feline Thyrotropin Receptor (TSHR) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 86.6 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Feline
Expression System E.coli
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 86.6 kDa
Physical State Lyophilized
Formulation Tris/PBS-based buffer, 6% Trehalose.

Target Information

The feline thyrotropin receptor (TSHR) is a G protein-coupled receptor located on the surface of thyroid follicular epithelial cells. It binds to thyroid-stimulating hormone (TSH) to activate intracellular signaling pathways, promoting the synthesis and secretion of thyroid hormones (T3/T4). In feline hyperthyroidism (FHT), abnormal activation or mutations in TSHR may lead to excessive thyroid hormone secretion. TSHR also plays a role in thyroid cell proliferation and differentiation, which is essential for normal thyroid development and function.

Protein Feline Thyrotropin Receptor (TSHR)
Protein Synonym Thyroid-stimulating hormone receptor (TSH-R)
Gene ID 493842
UniProt ID Q9BGN4

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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