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Recombinant Feline Immunoglobulin Heavy Constant Epsilon (IgE Fc Fragment), C-His

Cat. No.AP3F7

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Feline Immunoglobulin Heavy Constant Epsilon (IgE Fc Fragment), C-His is a recombinant protein expressed from Mammalian Expression System. Its predicted molecular weight is 39.3 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Feline
Expression System Mammalian Expression System
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 39.3 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

Feline IGHE encodes the constant region of the immunoglobulin E (IgE) heavy chain. This isotype is the primary mediator of Type I hypersensitivity in cats and is essential for defense against helminth parasites. The Fc fragment specifically interacts with high-affinity receptors (Fc epsilon RI) on mast cells and basophils, triggering the degranulation and release of inflammatory mediators. It is a vital biomarker in veterinary research for diagnosing feline asthma, atopic dermatitis, and evaluating the efficacy of allergen-specific immunotherapy.

Protein Feline Immunoglobulin Heavy Constant Epsilon (IgE Fc Fragment)
Protein Synonym Feline IgE; IgE Fc Fragment; Immunoglobulin E Heavy Chain; C-epsilon; fIgE
UniProt ID A0A5F5XBY9

Shipping and Storage

This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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