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Recombinant Feline Beta-1 Adrenergic Receptor (ADRB1)
Product Overview
BioVenic's Recombinant Feline Beta-1 Adrenergic Receptor (ADRB1) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 50.5 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
The feline β1-adrenergic receptor (ADRB1) is a G protein-coupled receptor mainly found in the heart and adipose tissue, with equal sensitivity to epinephrine and norepinephrine. It regulates cardiac contractility, heart rate, and lipolysis by activating adenylate cyclase and increasing intracellular cAMP levels. Additionally, ADRB1 is involved in cold-induced thermogenesis, circadian rhythm regulation, and brown fat cell differentiation. Abnormal function of this receptor in cats may be associated with cardiovascular diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.