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Recombinant Equine Collagenase 3 (MMP13), N-His
Product Overview
BioVenic's Recombinant Equine Collagenase 3 (MMP13), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Equine collagenase 3, specifically Matrix Metalloproteinase 3 (MMP-3), is an enzyme that plays a critical role in the degradation of extracellular matrix (ECM) components, including proteoglycans, fibronectin, laminin, and collagen telopeptides. It is involved in tissue remodeling, wound healing, and the progression of various diseases such as arthritis and cancer. MMP-3 is also implicated in the inflammatory response and has been found to be upregulated in conditions like myocardial infarction and idiopathic pulmonary fibrosis, where it may contribute to tissue damage by cleaving proteins like E-cadherin.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.