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Recombinant Eastern Equine Encephalitis Virus (EEEV) Spike Glycoprotein E2, N-His
Product Overview
BioVenic's Recombinant Eastern Equine Encephalitis Virus (EEEV) Spike Glycoprotein E2, N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 42.7 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
E2 is the primary host-receptor binding protein of EEEV, organized as trimers of E1-E2 heterodimers on the virion surface. It facilitates neurotropism by interacting with cellular receptors such as VLDLR, ApoER2, and heparan sulfate proteoglycans. As the major target for neutralizing antibodies, E2 contains critical epitopes in its A and B domains that govern host range and pathogenicity. Its ability to facilitate rapid viral entry into the central nervous system makes it a central focus for vaccine design and therapeutic intervention.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.