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Recombinant Eastern Equine Encephalitis Virus (EEEV) Spike Glycoprotein E1, N-His
Product Overview
BioVenic's Recombinant Eastern Equine Encephalitis Virus (EEEV) Spike Glycoprotein E1, N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 48.1 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
E1 is a class II viral fusion protein that constitutes the icosahedral scaffold of the EEEV envelope. It primarily mediates pH-dependent membrane fusion between the viral envelope and host endosomal membranes during entry. In the mature virion, E1 exists as an inactive heterodimer with E2; upon endocytosis and acidification, the dimer dissociates, allowing E1 to form a stable homotrimer that inserts its fusion peptide into the host membrane. Its high conservation across alphaviruses makes it a prime target for broad-spectrum neutralizing antibodies and fusion-inhibiting therapeutics.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.