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Recombinant Dirofilaria Immitis Glutathione Peroxidase (DIT33), C-His
Product Overview
BioVenic's Recombinant Dirofilaria Immitis Glutathione Peroxidase (DIT33), C-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 25.0 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Glutathione peroxidase (GPx) is a vital antioxidant enzyme secreted by Dirofilaria immitis to facilitate its survival within the host's vascular system. It protects the parasite from oxidative damage by catalyzing the reduction of hydrogen peroxide and lipid hydroperoxides, effectively neutralizing the reactive oxygen species (ROS) produced by host neutrophils and macrophages. As an essential component of the filarial redox signaling and defense machinery, it represents a promising target for both diagnostic assays and chemotherapeutic intervention.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.