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Recombinant Classical Swine Fever Virus N-terminal Protease (CSFV N-Pro), C-His
Product Overview
BioVenic's Recombinant Classical Swine Fever Virus N-terminal Protease (CSFV N-Pro), C-His is a recombinant protein expressed from Insect Cells. Its predicted molecular weight is 20.0 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
N-pro (N-terminal autoprotease) is the first protein translated from the CSFV polyprotein. It possesses a unique autocatalytic activity, cleaving itself from the nascent polyprotein at the C-terminus. Beyond its proteolytic role, N-pro is a potent interferon (IFN) antagonist. It promotes the degradation of Interferon Regulatory Factor 3 (IRF3) via the proteasome pathway, effectively suppressing the host's innate immune response. This dual function as both an enzyme and an immune-evasion factor is vital for establishing persistent viral infection.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.