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Recombinant Classical Swine Fever Virus Glycoprotein E0 (CSFV gp44/48), N-His-SUMO

Cat. No.VG3F190

Product TypeVeterinary Antigens

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Product Overview

BioVenic's Recombinant Classical Swine Fever Virus Glycoprotein E0 (CSFV gp44/48), N-His-SUMO is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 39.0 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Virus
Expression System E.coli Expression System
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 39.0 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

Erns (formerly E0) is a unique structural glycoprotein of Classical Swine Fever Virus. Unlike E1 and E2, it lacks a typical membrane anchor and is both virion-associated and secreted from infected cells. It possesses intrinsic RNase activity (T2 RNase family), which is a key virulence factor that suppresses host innate immunity by degrading viral dsRNA and inhibiting Type I Interferon (IFN-alpha/beta) production. Additionally, Erns mediates initial viral attachment by binding to cellular heparan sulfate and laminin receptors.

Protein Classical Swine Fever Virus Glycoprotein E0
Protein Synonym Erns; gp44/48; E0 protein; Ribonuclease Erns; Pestivirus Erns
UniProt ID O72430

Shipping and Storage

This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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