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Recombinant Chikungunya Virus Spike Glycoprotein E1, C-Fc
Product Overview
BioVenic's Recombinant Chikungunya Virus Spike Glycoprotein E1, C-Fc is a recombinant protein expressed from Mammalian Expression System. Its predicted molecular weight is 73.1 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
The E1 glycoprotein is a class II viral fusion protein essential for Chikungunya virus entry into host cells. It facilitates pH-dependent membrane fusion within the endosome following receptor-mediated endocytosis. E1 forms a heterodimer with the E2 protein on the viral surface, forming the characteristic spikes. During infection, the acidic environment triggers E1 dissociation from E2 and its subsequent insertion into the host membrane, making it a primary target for neutralizing antibodies and fusion-inhibitor drug development.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.