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Recombinant Chikungunya Virus Non-Structural Protein 3 (NSP3), N-His
Product Overview
BioVenic's Recombinant Chikungunya Virus Non-Structural Protein 3 (NSP3), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 19.5 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
nsP3 is a multi-domain accessory protein essential for the assembly and function of the viral replication complex (vRC). It consists of a conserved N-terminal macrodomain with ADP-ribosyl hydrolase activity, a central zinc-binding alphavirus-unique domain (AUD), and a C-terminal hypervariable domain (HVD). nsP3 acts as a critical scaffold, recruiting host factors like G3BP and NAP1 to viral replication sites. It modulates the host's innate immune response and is a major determinant of viral neurovirulence and vector specificity.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.