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Recombinant Chikungunya Virus Antigen
Product Overview
BioVenic's Recombinant Chikungunya Virus Antigen is a recombinant antigen produced by E.coli. This antigen has undergone a rigorous purification process. It can be used for ELISA plate coating or for the preparation of enzyme conjugates.
Specifications
Target Information
Chikungunya Virus (CHIKV) is an enveloped, positive-sense, single-stranded RNA virus belonging to the genus Alphavirus within the Togaviridae family. Transmitted to humans primarily by Aedes mosquitoes (A. aegypti and A. albopictus), it causes chikungunya fever, an acute illness characterized by high fever and severe, often debilitating polyarthralgia. The virus exhibits a strong tropism for fibroblasts, skeletal muscle progenitor cells, and synovial tissues. Key targets for molecular diagnostics, serological assays, and vaccine candidates include the structural envelope glycoproteins, specifically E1 and E2. The E2 protein is responsible for host cell receptor attachment and contains the dominant neutralizing epitopes, while the E1 protein facilitates pH-dependent membrane fusion within the endosome.
Shipping and Storage
This product is shipped with gel ice bags. Store at 0-4°C for no more than 2 weeks, or -20°C or below for long-term storage.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.