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Recombinant Chicken Urokinase-Type Plasminogen Activator (PLAU), N-His

Cat. No.AP1C374

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Chicken Urokinase-Type Plasminogen Activator (PLAU), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 49.4 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Chicken
Expression System E.coli
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 49.4 kDa
Physical State Lyophilized
Formulation The buffer before lyophilization is PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

Target Information

Chicken Urokinase-type plasminogen activator (PLAU) is a serine protease that primarily functions to convert plasminogen into plasmin, facilitating the degradation of the extracellular matrix to aid cell migration and tissue remodeling. In chickens, PLAU is involved in the degradation of the follicle wall, particularly during the rupture of pre-ovulatory follicles. Additionally, the expression of the PLAU gene is regulated by multiple signaling pathways, such as protein tyrosine kinase pp60v-src and protein kinase C, which show significant induction in Rous sarcoma virus (RSV)-transformed chicken cells.

Protein Chicken Urokinase-Type Plasminogen Activator (PLAU)
Protein Synonym U-plasminogen activator; uPA
Gene ID 396424
UniProt ID P15120

Shipping and Storage

This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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