Recombinant Chicken Solute Carrier Family 2, Facilitated Glucose Transporter Member 3 (SLC2A3)

Chicken Solute Carrier Family 2, Facilitated Glucose Transporter Member 3 (SLC2A3), also known as GLUT3, is a key membrane protein involved in glucose transport across the cell membrane. It facilitates the uptake of glucose and other monosaccharides, playing a crucial role in maintaining cellular energy metabolism. In chickens, SLC2A3 is highly expressed in the central nervous system, similar to its role in mammals, where it supports neuronal function and energy homeostasis. Additionally, SLC2A3 is involved in the formation of tight junctions in the blood-retinal barrier, highlighting its importance in maintaining tissue integrity. Abnormal expression of SLC2A3 has been implicated in various diseases, including cancer, where it can promote tumor growth and metastasis by enhancing glucose uptake and metabolism. In chickens, the upregulation of SLC2A3 may also be associated with metabolic adaptations and tissue-specific functions, making it a potential target for studying metabolic disorders and cancer biology.