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Recombinant Chicken Phosphatidylcholine-Sterol Acyltransferase (LCAT)
Product Overview
BioVenic's Recombinant Chicken Phosphatidylcholine-Sterol Acyltransferase (LCAT) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 47.8 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Chicken Phosphatidylcholine-Sterol Acyltransferase (LCAT) is a key enzyme involved in lipid metabolism, particularly in the esterification of cholesterol. LCAT catalyzes the conversion of free cholesterol to cholesteryl esters, which are then incorporated into high-density lipoproteins (HDL) and low-density lipoproteins (LDL). This process is crucial for the reverse cholesterol transport (RCT) pathway, which helps remove excess cholesterol from peripheral tissues and deliver it to the liver for excretion. In chickens, LCAT is primarily synthesized in the liver and is essential for maintaining cholesterol homeostasis. Abnormal expression or function of LCAT can lead to lipid metabolic disorders, including hypercholesterolemia and atherosclerosis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.