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Recombinant Chicken Interleukin 17 (IL-17), N-His-GST
Product Overview
BioVenic's Recombinant Chicken Interleukin 17 (IL-17), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 46.3 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
In chickens, interleukin-17 (IL-17) plays a crucial role in the immune system, particularly in regulating inflammatory responses and host defense. IL-17 activates immune cells, such as macrophages and T cells, enhancing the body's defense against pathogens. Additionally, IL-17 is involved in regulating the expression of antimicrobial peptides, such as β-defensins and cathelicidins, thereby enhancing the antimicrobial capacity of the intestinal mucosa. Studies have shown that IL-17 can significantly reduce the severity of necrotic enteritis (NE) lesions in the chicken intestine by modulating the expression of antimicrobial peptides, thus enhancing defense against pathogens.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.