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Recombinant Chicken Guanylyl Cyclase-Activating Protein 2 (GUCA1B)

Cat. No.AP2C318

Product TypeAnimal Proteins

Size

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Product Overview

BioVenic's Recombinant Chicken Guanylyl Cyclase-Activating Protein 2 (GUCA1B) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 23.1 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Chicken
Expression System E.coli
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 23.1 kDa
Physical State Lyophilized
Formulation Tris/PBS-based buffer, 5%-50% glycerol.

Target Information

Chicken guanylyl cyclase-activating protein 2 (GUCA1B) is a calcium-binding protein that plays a key role in the retina. It regulates cGMP synthesis by activating retinal guanylyl cyclases (RetGCs) under low calcium ion conditions and inhibiting them under high calcium levels. This mechanism is crucial for photoreceptor recovery from light stimulation. Mutations in GUCA1B can lead to retinal dystrophies, including retinitis pigmentosa.

Protein Chicken Guanylyl Cyclase-Activating Protein 2 (GUCA1B)
Protein Synonym GUCA1B; GCAP2; Guanylyl cyclase-activating protein 2; GCAP 2; Guanylate cyclase activator 1B
Gene ID 419864
UniProt ID P79881

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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