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Recombinant Chicken Cerberus (CAR), C-hFc-Active
Product Overview
BioVenic's Recombinant Chicken Cerberus (CAR), C-hFc-Active is a recombinant protein expressed from Mammalian Expression System. Its predicted molecular weight is . The purity is>90% (SDS-PAGE).
Specifications
Target Information
Chicken CAR (Caronte) is a secreted glycoprotein and a member of the Cerberus/DAN family of BMP antagonists. It plays a fundamental role in avian embryonic development by establishing left-right asymmetry. Specifically, Caronte is induced by Sonic hedgehog (Shh) in the left paraxial mesoderm, where it binds to and inhibits Bone Morphogenetic Proteins (BMPs). This antagonism releases the repression on Nodal and Lefty genes, ensuring the proper lateralization of internal organs like the heart and stomach during morphogenesis.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
