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Recombinant Canine Programmed Cell Death Protein 1 (PD1), C-His
Product Overview
BioVenic's Recombinant Canine Programmed Cell Death Protein 1 (PD1), C-His is a recombinant protein expressed from Mammalian Expression System. Its predicted molecular weight is 19.2 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Canine CD279, also known as PD-1, is a key immune checkpoint receptor expressed on activated T cells, B cells, and myeloid cells in dogs. It functions as a negative regulator of the adaptive immune response by interacting with its ligands, PD-L1 and PD-L2, to prevent excessive inflammation and autoimmunity. In veterinary oncology, CD279 is a primary target for immunotherapy; blocking its signaling can reverse T-cell exhaustion, enhancing the immune system's ability to eradicate malignant tumors like oral melanoma and osteosarcoma.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.