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Recombinant Canine Lymphocyte Activating 3 (LAG3), C-His
Product Overview
BioVenic's Recombinant Canine Lymphocyte Activating 3 (LAG3), C-His is a recombinant protein expressed from HEK293 Cells. Its predicted molecular weight is 46.8 kDa. The purity is>95% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL).
Specifications
Target Information
Lymphocyte activating 3 is encoded by the LAG3 gene in dogs. It has emerged as an eminent target in the development of cancer treatment and holds substantial prognostic value. LAG-3 is closely related to CD4, with which it shares the ability to bind MHC class II molecules.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Lecocq, Q. et al. The next-generation immune checkpoint LAG-3 and its therapeutic potential in oncology: Third time's a charm. International journal of molecular sciences. 2020, 22: 1867.