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Recombinant Canine Interleukin-1 Receptor Antagonist Protein (IL1RN)
Product Overview
BioVenic's Recombinant Canine Interleukin-1 Receptor Antagonist Protein (IL1RN) is a recombinant protein expressed from Pichia pastoris. Its predicted molecular weight is 17.5 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Canine interleukin-1 Receptor Antagonist Protein (IL1RN) is a crucial modulator in the immune response, particularly in the inhibition of interleukin-1 (IL-1) activity. It binds to the IL-1 receptor (IL1R1) and prevents the association with the coreceptor IL1RAP, thereby blocking the pro-inflammatory effects of IL-1. In dogs, IL1RN plays a significant role in managing inflammation and acute-phase responses, and it is secreted by various cells to maintain immune homeostasis.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute at 350 μg/mL in PBS.Aliquote the reconstituted solution to minimise freeze-thaw cycles.