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Recombinant Canine High Mobility Group Protein B1 (HMGB1), N-His
Product Overview
BioVenic's Recombinant Canine High Mobility Group Protein B1 (HMGB1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Canine high mobility group protein B1 (HMGB1) is a nuclear protein that plays a significant role in various physiological and pathological processes. It is involved in DNA damage repair, immune responses, inflammation, and cell survival. HMGB1 acts as a cytokine when released extracellularly, activating immune cells and promoting inflammation. It also contributes to the maintenance of genomic stability and the regulation of gene expression within the nucleus. In dogs, HMGB1 is expressed in nearly all cells and tissues, and its dysregulation is associated with various diseases, including infections, autoimmune conditions, and cancer.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.