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Recombinant Canine Hepatocyte Growth Factor (HGF)

Cat. No.AP7F446

Product TypeAnimal Proteins

Size 50 μg

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Product Overview

BioVenic's Recombinant Canine Hepatocyte Growth Factor (HGF) is a recombinant protein expressed from HEK293 Cells. Its predicted molecular weight is 79.9 kDa. The purity is>95% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL).

Specifications

Type Recombinant Protein
Species Canine
Expression System HEK293 Cells
Biological Activity Active
Purity >95% (SDS-PAGE)
Endotoxin <1 EU/μg (LAL)
Predicted Molecular Weight 79.9 kDa
Physical State Lyophilized
Formulation PBS, pH 7.4.

Target Information

Hepatocyte growth factor is encoded by the HGF gene in dogs. HGF activates the proto-oncogenic receptor tyrosine kinase c-MET and subsequent down-stream pathways, including the anti-apoptotic protein kinase-B (PKB/Akt) cascade, the proliferative MAP-kinase pathway (ERK1/2 and p38MAPK), and the STAT3 signaling (signal transducers and activators of transcription).

Protein Canine Hepatocyte Growth Factor (HGF)
Protein Synonym hepatocyte growth factor, SF, hepatopoeitin-A, hepatopoietin-A, scatter factor
Gene ID 403441
UniProt ID Q867B7

Shipping and Storage

This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.

References

  1. Spee, B. et al. Major HGF-mediated regenerative pathways are similarly affected in human and canine cirrhosis. Comparative hepatology. 2007, 6: 8.
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