This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Canine Elastase, Neutrophil Expressed (ELANE), N-His
Product Overview
BioVenic's Recombinant Canine Elastase, Neutrophil Expressed (ELANE), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 27.0 kDa. The purity is> 95%.
Specifications
Target Information
Canine Elastase, Neutrophil Expressed (ELANE) is a serine protease found in neutrophil granules, playing a key role in innate immune defense. It hydrolyzes proteins within neutrophil azurophil granules and the extracellular matrix. ELANE is crucial for neutrophil function, including microbial killing and inflammation regulation. Mutations in the ELANE gene can lead to severe congenital neutropenia and cyclic neutropenia, conditions characterized by low neutrophil counts and increased susceptibility to infections. In research, ELANE is used to study neutrophil biology, immune responses, and the pathogenesis of neutropenia. It also has potential applications in understanding and treating related immune disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-0.5 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.