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Recombinant Canine CD40 ligand (CD40LG), N-Fc

Cat. No.AP2C51

Product TypeAnimal Proteins

Size 100 μg

Product Overview

BioVenic's Recombinant Canine CD40 ligand (CD40LG), N-Fc is a recombinant protein expressed from HEK293 Cell. Its predicted molecular weight is 42.5 kDa. The purity is>85% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Canine
Expression System HEK293 Cell
Purity >85% (SDS-PAGE)
Predicted Molecular Weight 42.5 kDa
Physical State Lyophilized
Formulation pH 7.4. 5 % trehalose and mannitol are added as protectants.

Target Information

In canines, CD40 ligand (CD40LG) is an important immune regulatory protein expressed by activated T cells. It induces the maturation of immature dendritic cells (DCs) and activates immune cells by binding to CD40, promoting B cell antibody class switching, memory B cell development, and germinal center formation. Additionally, CD40LG plays a significant role in cancer immunotherapy. For example, adenoviral vector-mediated CD40LG gene therapy has shown promising results in canine malignant melanoma treatment by inducing T and B cell infiltration in tumor tissues

Protein Canine CD40 ligand (CD40LG)
Protein Synonym CD154; CD40LG; TNFSF5
Gene ID 403468
UniProt ID O97626

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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