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Recombinant Canine C-C Motif Chemokine 2 (CCL2), N-His-GST
Product Overview
BioVenic's Recombinant Canine C-C Motif Chemokine 2 (CCL2), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 41.2 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Canine C-C motif chemokine 2 (CCL2), also known as monocyte chemoattractant protein-1 (MCP-1), is a chemokine that primarily attracts monocytes, memory T cells, and natural killer cells. It plays a crucial role in the immune response to inflammation and infection by directing the migration of these immune cells to sites of injury or infection. CCL2 is also involved in the recruitment of regulatory T cells (Tregs) to tumor sites, which can suppress anti-tumor immune responses and is a significant factor in the immunosuppressive tumor microenvironment.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquote as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL.Aliquote the reconstituted solution to minimise freeze-thaw cycles.