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Recombinant Brucella suis biovar 1 Response Regulator Transcription Factor, N-His
Product Overview
BioVenic's Recombinant Brucella suis biovar 1 Response Regulator Transcription Factor, N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 27.9 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
BvrR is a pivotal response regulator that, along with its cognate sensor kinase BvrS, forms a master two-component system essential for the virulence of Brucella suis. It orchestrates the transition from free-living to an intracellular lifestyle by regulating the expression of outer membrane proteins (Omps), such as Omp25 and Omp22, and controlling the Type IV Secretion System (VirB). By sensing environmental cues like pH changes and nutrient availability, BvrR ensures cell envelope homeostasis and successful replication within host macrophages.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.