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Recombinant Bovine Tuberculosis ESAT-6:CFP-10 Fusion Antigen
Product Overview
BioVenic's Recombinant Bovine Tuberculosis ESAT-6:CFP-10 Fusion Antigen is a recombinant antigen produced by E.coli. This antigen has undergone a rigorous purification process. It can be used for ELISA plate coating or for the preparation of enzyme conjugates.
Specifications
Target Information
The ESAT-6:CFP-10 Fusion Antigen is a recombinant protein linking two highly immunodominant virulence factors secreted by the ESX-1 system of Mycobacterium bovis and Mycobacterium tuberculosis. Located within the Region of Difference 1 (RD1) genomic segment, these proteins form a tight 1:1 helical complex essential for macrophage membrane disruption. Because RD1 is absent in all M. bovis BCG vaccine strains and most environmental non-tuberculous mycobacteria, this fusion antigen serves as a critical, highly specific marker in interferon-gamma release assays (IGRAs) and skin tests to accurately differentiate bovine tuberculosis-infected livestock from vaccinated or environmentally sensitized animals.
Shipping and Storage
This product is shipped with gel ice bags. Store at 0-4°C for no more than 2 weeks, or -20°C or below for long-term storage.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.