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Recombinant Bovine Protein-S100-A4 (S100A4), N-His
Product Overview
BioVenic's Recombinant Bovine Protein-S100-A4 (S100A4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 13.1 kDa. The purity is> 97%.
Specifications
Target Information
Bovine Protein-S100-A4 (S100A4) is a member of the S100 calcium-binding protein family, known for its roles in cell motility, invasion, and fibrotic processes. In bovine systems, S100A4 is expressed in various cell types, including immune cells like macrophages and fibroblasts. It has been implicated in promoting inflammation and fibrosis, which are critical in diseases such as endometritis. S100A4 can also influence the progression of fibrosis in organs like the liver and lungs by activating fibroblasts and promoting extracellular matrix (ECM) production. Additionally, S100A4 has been shown to interact with receptors such as TLR4, contributing to inflammatory responses. In research, S100A4 is used as a biomarker and therapeutic target for fibrotic and inflammatory conditions.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.