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Recombinant Bovine Prokineticin-2 (PROK2), N-His
Product Overview
BioVenic's Recombinant Bovine Prokineticin-2 (PROK2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine-prokineticin 2 (PK2) is a regulatory peptide that belongs to the prokineticin family, which also includes prokineticin 1 (PK1). PK2 is known to bind to two G-protein-coupled receptors, PKR1 and PKR2, and is involved in a variety of physiological functions in cattle. It plays a role in immune regulation, inflammation, and bone metabolism. PK2 is also reported to be an output molecule for the suprachiasmatic nucleus (SCN) clock, which is the central circadian pacemaker in mammals. In cattle, PK2 expression is highly circadian and regulated by the central clock machinery. It is involved in the regulation of locomotion, sleep/wake cycle, body temperature, food intake, hormone levels, emotional conditions, and energy metabolism.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.