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Recombinant Bovine Platelet Factor 4 (PF4), N-His
Product Overview
BioVenic's Recombinant Bovine Platelet Factor 4 (PF4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 13.2 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Bovine platelet factor 4 (PF4) is a small chemokine protein that is rapidly secreted by activated platelets. It is known for its role in promoting blood coagulation and has a significant function in innate and adaptive immunity, especially when platelets are activated in response to infections. PF4 contributes to the recruitment of neutrophils and facilitates neutrophil exocytosis to release myeloperoxidase and lysozyme. It also stimulates antigen-presenting cells to induce lymphocyte proliferation and the cytotoxic activity of NK cells, playing a critical role in the clearance of viruses.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.