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Recombinant Bovine Peptidyl-Prolyl Cis-trans Isomerase FKBP1B (FKBP1B), N-His
Product Overview
BioVenic's Recombinant Bovine Peptidyl-Prolyl Cis-trans Isomerase FKBP1B (FKBP1B), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 15.4 kDa. The purity is> 90%.
Specifications
Target Information
Bovine Peptidyl-Prolyl Cis-trans Isomerase FKBP1B (FKBP1B) is a member of the FKBP family, primarily expressed in myocardium, brain tissue, and smooth muscle. It functions as a peptidyl-prolyl cis-trans isomerase, facilitating protein folding and stability. FKBP1B plays a crucial role in regulating calcium release by binding to the RyR2 receptor, which is essential for calcium-induced calcium release (CICR) in the sarcoplasmic reticulum. This protein is implicated in heart development, disease, brain aging, and nerve dysfunction. In bovine systems, FKBP1B is vital for maintaining normal cardiac and neurological functions, and its dysfunction can lead to severe cardiovascular and neurological disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.