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Recombinant Bovine Oxidized Low-density Lipoprotein Receptor 1 (OLR1), N-His
Product Overview
BioVenic's Recombinant Bovine Oxidized Low-density Lipoprotein Receptor 1 (OLR1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 28.5 kDa. The purity is> 97%.
Specifications
Target Information
Bovine oxidized low-density lipoprotein receptor 1 (OLR1), also known as LOX-1, is a receptor that mediates the recognition, internalization, and degradation of oxidatively modified low-density lipoprotein (oxLDL) by vascular endothelial cells. It plays a significant role in atherosclerosis, a condition characterized by the thickening and lipid accumulation in arterial walls. The receptor is particularly active in large arteries and is up-regulated under pro-atherogenic conditions such as hypertension, diabetes, and atherosclerosis itself. Furthermore, OLR1 has been implicated in the recognition and clearance of apoptotic cells, contributing to vascular health and homeostasis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.