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Recombinant Bovine Interleukin-18 (IL18), N-His
Product Overview
BioVenic's Recombinant Bovine Interleukin-18 (IL18), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 21.8 kDa. The purity is>95% (SDS-PAGE).
Specifications
Target Information
Bovine interleukin 18 (IL18) is a pro-inflammatory cytokine that plays a pivotal role in the immune system of cattle. IL18 is involved in the activation of natural killer (NK) cells and T cells, particularly Th1 cells, leading to the production of interferon-gamma (IFN-γ). This protein is multifunctional, promoting inflammation, angiogenesis, and having a role in the pathogenesis of various diseases, including autoimmune conditions and cancer. IL18 also contributes to the regulation of glucose homeostasis and can influence insulin secretion by pancreatic beta cells. The balance of IL18 is critical, as its dysregulation can lead to chronic inflammatory diseases. Its role in immune modulation makes IL18 a significant factor in both physiological and pathological conditions in cattle.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.