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Recombinant Bovine Cystatin-B (CSTB), N-His
Product Overview
BioVenic's Recombinant Bovine Cystatin-B (CSTB), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 12.4 kDa. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine cystatin-B is an intracellular inhibitor of papain-like cysteine proteinases, belonging to the cystatin family 1, also known as stefins. It is a tight-binding, reversible inhibitor that plays a role in regulating the activity of cathepsins, particularly within the lysosomal system. In cattle, Cystatin-B helps prevent uncontrolled proteolysis, which can be damaging to cells, and it is implicated in various pathological conditions, including neurodegenerative diseases and cancer.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.