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Recombinant Bovine Collagen Alpha-2(I) Chain (COL1A2), N-His
Product Overview
BioVenic's Recombinant Bovine Collagen Alpha-2(I) Chain (COL1A2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is N/A. The purity is>97% (SDS-PAGE).
Specifications
Target Information
Bovine collagen alpha-2(I) chain is a component of type I collagen, a major structural protein in the extracellular matrix of various connective tissues in cattle. This protein is crucial for tissue integrity and provides strength and flexibility. It is a part of the heterotrimeric collagen molecule, which includes two alpha-1 chains and one alpha-2 chain. The alpha-2(I) chain, along with other chains, contributes to the formation of collagen fibrils, which are essential for the structural organization of tissues such as skin, tendon, bone, and organ basement membranes. Mutations in the gene encoding this protein have been associated with various diseases, including osteogenesis imperfecta. In the context of cattle, it plays a significant role in animal health, development, and could be a factor in meat and leather quality/
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.