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Recombinant Bovine Caspase 8 (CASP8), N-His
Product Overview
BioVenic's Recombinant Bovine Caspase 8 (CASP8), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 19.4 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Bovine caspase 8 is a cysteine-dependent aspartate-specific protease that plays a critical role in the extrinsic apoptosis pathway. It is activated by the death receptor signaling and initiates a cascade involving effector caspases, leading to cell death. Caspase 8 also interacts with regulatory proteins, modulating cell survival and apoptosis. It is crucial for immune homeostasis and has potential therapeutic implications in diseases characterized by aberrant apoptotic signaling.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.