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Recombinant Bovine 7-Dehydrocholesterol Reductase (DHCR7), N-His
Product Overview
BioVenic's Recombinant Bovine 7-Dehydrocholesterol Reductase (DHCR7), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 55.8 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Bovine 7-dehydrocholesterol reductase (DHCR7) is a key enzyme in the cholesterol biosynthesis pathway in cattle, catalyzing the conversion of 7-dehydrocholesterol to cholesterol.This process is not only vital for maintaining cellular membrane integrity and function but also plays a role in the development and health of the Bovine organism. Disruption of DHCR7 can lead to an accumulation of 7-dehydrocholesterol, which may have broader implications for cellular processes, including the modulation of ferroptosis, a form of regulated cell death.Understanding the role of DHCR7 in cattle is essential for studying cholesterol metabolism and its related physiological and pathological processes in veterinary medicine and animal health.
Shipping and Storage
This product is shipped with dry ice. It is recommended to aliquot as needed and store at -80°C upon receipt. Reconstituted protein solution can be stored at 4°C for 1 week, at < -80°C for 12 months. Avoid repeated freezing and thawing.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimise freeze-thaw cycles.