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Recombinant Borreliella burgdorferi Complement Regulator-Acquiring Surface Protein 1 (CRASP-1) (cspA), MBP
Product Overview
BioVenic's Recombinant Borreliella burgdorferi Complement Regulator-Acquiring Surface Protein 1 (CRASP-1) (cspA), MBP is a recombinant protein expressed from E.coli. Its predicted molecular weight is 29.1 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
The Borreliella burgdorferi complement regulator-acquiring surface protein 1 (CRASP-1) (cspA) is a surface lipoprotein that plays a crucial role in the bacterium's ability to evade the host's immune system. It binds to host complement regulators such as factor H, which helps the bacterium avoid complement-mediated killing. In veterinary medicine, understanding CRASP-1's function is important for developing strategies to combat Lyme disease. It is used in diagnostic tests to detect antibodies in animals that have been exposed to the bacterium, aiding in the early detection and management of the disease
. Additionally, CRASP-1 is a target for vaccine development, as blocking its function can potentially prevent the bacterium from establishing infection.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.