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Recombinant Borreliella burgdorferi Complement Regulator-Acquiring Surface Protein 2 (CRASP-2) (cspZ), MBP
Product Overview
BioVenic's Recombinant Borreliella burgdorferi Complement Regulator-Acquiring Surface Protein 2 (CRASP-2) (cspZ), MBP is a recombinant protein expressed from E.coli. Its predicted molecular weight is 27.2 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Borreliella burgdorferi complement regulator-acquiring surface protein 2 (CRASP-2) (cspZ) is a surface lipoprotein that binds to host complement regulators such as factor H and factor H-like protein 1 (FHL-1). This interaction helps the bacterium evade the host's immune system by inhibiting the activation of the complement system, which is crucial for the bacterium's survival in mammalian hosts. In veterinary medicine, CRASP-2 is used in diagnostic tests to detect antibodies in animals that have been exposed to the bacterium, aiding in the early detection and management of Lyme disease. Additionally, understanding the function of CRASP-2 can contribute to the development of strategies to combat the disease.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.Aliquote the reconstituted solution to minimise freeze-thaw cycles.