Recombinant African Swine Fever Virus Ubiquitin-Conjugating Enzyme E2 (UBC), N-His

African swine fever virus ubiquitin-conjugating Enzyme E2 (UBC), also known as UBCv1, is a viral enzyme that plays a critical role in the viral replication cycle and modulation of host protein synthesis. UBCv1 is expressed early in infection and is involved in the conjugation of ubiquitin to target proteins, which can lead to their degradation or alteration in function. This enzyme interacts with the host translation machinery, impacting the mTORC signaling pathway and regulation of host translation, thereby potentially contributing to the virus's ability to evade host immune responses. In veterinary medicine, understanding UBCv1's function is essential for developing strategies against ASFV, as it may serve as a target for antiviral therapies and vaccine development.