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Recombinant African Swine Fever Virus Lectin-like Protein EP153R (EP153R), C-Fc
Product Overview
BioVenic's Recombinant African Swine Fever Virus Lectin-like Protein EP153R (EP153R), C-Fc is a recombinant protein expressed from Mammalian Expression System. Its predicted molecular weight is 41.4 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
EP153R is a non-structural, type II transmembrane glycoprotein of the African Swine Fever Virus (ASFV) that plays a sophisticated role in host immune evasion and viral dissemination. It contains a specialized C-type lectin-like domain (CTLD), a feature typically found in host immune receptors like CD69 or NK cell receptors. EP153R functions as a multi-modal suppressor of host defenses, primarily by inhibiting apoptosis and interfering with the presentation of viral antigens to the immune system. While not essential for viral replication in vitro, it is a significant virulence factor in vivo and is renowned for its role in the "hemadsorption" phenomenon.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.