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Recombinant African Swine Fever Virus E184L Protein (E184L), C-His
Product Overview
BioVenic's Recombinant African Swine Fever Virus E184L Protein (E184L), C-His is a recombinant protein expressed from Insect Cells. Its predicted molecular weight is 22.7kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
E184L is a critical early-stage regulatory protein in the African Swine Fever Virus (ASFV) genome. It functions as a DNA repair enzyme with apurinic/apyrimidinic (AP) endonuclease activity, playing a vital role in maintaining viral genomic integrity during replication within the host macrophage's oxidative environment. By facilitating the base excision repair (BER) pathway, E184L protects the virus from DNA damage, making it a significant target for developing live-attenuated vaccines and antiviral inhibitors aimed at reducing viral virulence.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.