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Recombinant African Swine Fever Virus Cysteine Protease S273R (ASFV S273R), N-His
Product Overview
BioVenic's Recombinant African Swine Fever Virus Cysteine Protease S273R (ASFV S273R), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 33.7 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
S273R is a vital 31-kDa cysteine protease of African Swine Fever Virus (ASFV) belonging to the SUMO-1-specific protease family.2 It plays a dual role in the viral life cycle: primarily, it catalyzes the proteolytic processing of polyproteins pp220 and pp62 into mature structural proteins (p150, p37, p34, p15, p35) essential for core-shell assembly. Additionally, S273R acts as a potent immune antagonist by inhibiting the cGAS-STING and NF-4 kappa B pathways, facilitating viral evasion of host innate immunity. Its indispensability makes it a prime target for antiviral drug and vaccine development.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.