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Recombinant African Swine Fever Virus A179L Protein (ASFV A179L), N-His
Product Overview
BioVenic's Recombinant African Swine Fever Virus A179L Protein (ASFV A179L), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 19.4 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
A179L is a highly conserved viral homolog of the anti-apoptotic Bcl-2 protein, essential for African Swine Fever Virus (ASFV) virulence. It functions by binding to and neutralizing pro-apoptotic BH3-only proteins and the autophagy regulator Beclin-1, thereby suppressing premature host cell death and autophagy. By maintaining cell viability during the replication cycle, A179L ensures maximal viral progeny production and facilitates immune evasion. Its pivotal role in manipulating host cell survival pathways makes it a key target for studying viral pathogenesis and developing attenuated vaccines.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.