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Rabbit Anti-Rat Tumor Protein p53 (P53) Polyclonal Antibody

Cat. No.VD1N66

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat tumor protein p53. It is affinity purified by protein A. It can be applied to WB and ICC/IF assays of rat tumor protein p53.

Specifications

Application WB; ICC/IF
Clonality Polyclonal
Classification Primary Antibody
Clone A2N8
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Tumor Protein p53
Isotype IgG
Immunogen Recombinant protein of rat tumor protein p53
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Rat Tumor Protein p53 (P53) is a critical transcription factor encoded by the Tp53 gene, which responds to various cellular stresses to regulate genes involved in cell cycle arrest, apoptosis, senescence, and DNA repair. It plays a central role in maintaining genomic stability and preventing tumorigenesis. P53 is typically stabilized and accumulates in response to DNA damage, where it binds to specific DNA sequences to activate target genes. Mutations in the Tp53 gene are frequently associated with cancer development, highlighting its importance as a tumor suppressor.

Target Rat Tumor Protein p53
Target Synonym TP53; LFS1; TRP53; Li-Fraumeni Syndrome; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
Gene ID 24842
UniProt ID P10361

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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