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Rabbit Anti-Rat Tumor Necrosis Factor Alpha (TNFa) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat tumor necrosis factor alpha. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat tumor necrosis factor alpha.
Specifications
Target Information
Rat Tumor Necrosis Factor Alpha (TNFa) is a pro-inflammatory cytokine produced primarily by macrophages and other immune cells. It plays a critical role in regulating immune responses, inflammation, and apoptosis. TNFa acts through two receptors, TNFR1 and TNFR2, triggering signaling pathways that lead to the activation of transcription factors like NF-κB. This cytokine is involved in various inflammatory and autoimmune diseases, making it an important target for therapeutic interventions.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Costelli, Paola, et al. "Tumor necrosis factor-alpha mediates changes in tissue protein turnover in a rat cancer cachexia model." The Journal of clinical investigation 92.6 (1993): 2783-2789.